Let's Talk About Herpes

Herpes simplex virus (HSV) is a common viral infection that may or may not cause immediate symptoms. There are two primary types: HSV-1 and HSV-2. Each type differs in transmission patterns and typical symptom locations.

Globally, more than half of adults have HSV-1, while HSV-2 affects a smaller but significant percentage of the population. Either type can infect oral or genital areas.

Herpes Simplex Virus Type 1 (HSV-1)

HSV-1 is most commonly transmitted through oral-to-oral contact. It typically causes oral herpes, often referred to as cold sores or fever blisters. These appear as painful, fluid-filled blisters around the mouth, lips, or gums.

Common HSV-1 Symptoms

• Tingling, itching, or burning around the mouth

• Small, painful blisters

• Crusted sores after blisters rupture

• Mild fever or general discomfort (especially during the first outbreak)

Symptoms usually appear 1–3 weeks after exposure, though many people never develop noticeable sores.

HSV-1 is not curable, but outbreaks often become less frequent and less severe over time. Antiviral medications can shorten outbreaks and reduce transmission risk.

Herpes Simplex Virus Type 2 (HSV-2)

HSV-2 is most commonly associated with genital herpes and is primarily transmitted through sexual contact. In some cases, HSV-1 can also cause genital herpes through oral-genital contact.

Common HSV-2 Symptoms

• Itching or tingling in the genital or anal area

• Painful blisters or open sores

• Fever, headache, or muscle aches (especially during the first outbreak)

• Swollen lymph nodes

• Pain with urination

Initial outbreaks usually occur 1–3 weeks after exposure and may last several weeks. Over time, outbreaks typically become less frequent and milder.

Herpes can be diagnosed through several methods, depending on symptoms and timing:

• PCR testing from a lesion (most accurate during active outbreaks)

• Viral culture from an open sore

• Blood tests to detect HSV-1 or HSV-2 antibodies (helpful for past exposure)

Testing is especially important for people with genital symptoms, multiple partners, or immunocompromising conditions.

There is no cure for herpes, but antiviral therapy is highly effective at managing the condition.

FDA-Approved Antiviral Medications

• Valacyclovir (Valtrex®)

• Acyclovir (Zovirax®)

• Famciclovir (Famvir®)

Treatment strategies include:

• Episodic therapy to shorten outbreaks

• Daily suppressive therapy to reduce outbreak frequency and lower transmission risk

Suppressive therapy can reduce transmission risk by up to 50% when combined with safer-sex practices.

How Call-On-Doc Can Help

If you are experiencing symptoms or believe you may have been exposed to herpes, Call-On-Doc offers fast, private, and affordable care.

Through Call-On-Doc, you can:

• Request discreet online evaluation

• Receive antiviral prescriptions quickly

• Access suppressive or outbreak treatment

• Avoid long wait times or in-person visits

Care is provided through secure online forms, phone calls, or video visits—so you can get treatment when you need it, without delay.