Published on Oct 11, 2021 | 2:58 PM
When it comes to respiratory illnesses, COVID-19 and the flu (influenza) share a lot in common. Both are highly contagious, spread in similar ways, and often produce overlapping symptoms.
Many people can find it nearly impossible to tell them apart just by how they feel, especially in the early stages of illness. This overlap is particularly problematic during flu season, when cases of both flu and COVID-19 spike, increasing the chances of infection with one or even both viruses.
Both COVID-19 and the flu can begin with mild symptoms that may gradually or suddenly worsen. They share common symptoms like fever, cough, and fatigue, making it easy to confuse the two.
Knowing the common differences between COVID-19 and the flu can help guide your decisions about treatment, isolation, and when to seek medical care. However, it’s important to remember testing is the most reliable way to confirm your diagnosis. Factors like vaccination status, virus variants, and overall health can also influence how you experience symptoms for both illnesses.

Although symptoms overlap, certain features can help differentiate the two:
Onset of symptoms:
COVID-19 symptoms usually develop gradually over 2–14 days
Flu symptoms tend to appear suddenly within 1–4 days
Unique symptoms:
COVID-19 is more likely to cause loss of taste or smell, diarrhea, shortness of breath, and prolonged fatigue
These symptoms are less common with the flu
Before testing, these questions may help guide your suspicion:
Did symptoms appear suddenly or gradually?
Flu symptoms often start abruptly and intensely, while COVID-19 symptoms typically build over several days.
Do you have a loss of taste or smell?
Sudden loss of taste or smell strongly suggests COVID-19 and is rare with the flu.
Have you been exposed to someone with COVID-19 or the flu?
Recent exposure can provide an important clue.
How long have symptoms lasted?
Flu symptoms usually resolve within 1–2 weeks. Symptoms that persist longer—especially fatigue or breathing issues—are more suggestive of COVID-19.
If you feel unwell, take the following steps to protect yourself and others:
Symptoms alone cannot reliably distinguish COVID-19 from the flu. Testing is the most accurate way to confirm your illness. Rapid tests are widely available. If symptoms persist despite a negative test, consider retesting or consulting a healthcare provider.
While awaiting results—or if you test positive—stay home, avoid close contact, and wear a mask when around others. Remain home until your fever has resolved without medication.
Inform people you’ve been in close contact with so they can monitor symptoms and take precautions.
Rest, hydration, and over-the-counter medications like acetaminophen or ibuprofen can help relieve mild symptoms. Providers can also help manage cough, congestion, and sore throat.
Seek emergency care immediately for:
Difficulty breathing
Chest pain
Confusion
Persistent high fever
Ongoing fatigue, cough, or shortness of breath—especially after COVID-19—may require further evaluation.
Are there other illnesses that mimic COVID-19 or the flu?
Yes. The common cold and RSV (respiratory syncytial virus) can cause similar symptoms. Colds are usually milder, while RSV more often causes wheezing or severe breathing problems, particularly in infants and older adults.
Can you have COVID-19 and the flu at the same time?
Yes. Co-infection is possible, especially during flu season.
How can I protect myself?
Stay up to date on COVID-19 vaccines and boosters, receive your annual flu vaccine, wash hands frequently, avoid close contact with sick individuals, and consider masking in crowded indoor settings—especially if you are high-risk.
When you’re sick, staying home is often the safest choice. Call-On-Doc offers fast, reliable online care for both COVID-19 and flu treatment.
If appropriate, providers can prescribe antiviral medications such as:
Paxlovid (nirmatrelvir) or Lagevrio (molnupiravir) for COVID-19
Tamiflu (oseltamivir) for influenza
Prescriptions are available in as little as 15 minutes, with no appointments required.
Skip in-person visits and recover at home. Start your online consultation today.
Sources:
English graduate and Call-On-Doc’s medical resource guide, Wayne C. Hahne is an experienced and passionate medical education content expert. Through diligent research, provider interviews and utilizing the industry's leading resources for wellness information, it is Mr. Hahne’s personal mission to educate the general public on medical conditions with in-depth and easy-to-understand written guides. updated 12/24/2025
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