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Pre-Travel Vaccine Checklist: The Essential Shots to Get Before Holiday Trips

Published on Nov 10, 2025 | 11:31 AM

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The holidays are all about connection—gathering with family, exploring new places, and maybe even traveling abroad. But with all that excitement comes one often overlooked step: making sure your vaccines are up to date. Whether you’re flying overseas or just visiting relatives across the country, vaccines are one of the best ways to protect yourself and your loved ones from getting sick on the road.

The Must-Have Basics Before You Travel

Even if you’re not leaving the country, there are a few vaccines you should be current on before stepping onto a plane or train:

  • Flu shot: Especially important for November and December travelers when flu season peaks.
  • COVID-19 booster: Updated vaccines help reduce the risk of serious illness from new variants.
  • Tdap (tetanus, diphtheria, pertussis): Needed every 10 years, protects against more than just cuts.
  • MMR (measles, mumps, rubella): Vital for anyone uncertain about immunity—important when traveling through busy airports.
     

These aren’t just about you—they protect the people you’re visiting, including grandparents, kids, and anyone with a weaker immune system.

 

Destination-Specific Vaccines You Might Need

If your travels take you outside the U.S., your checklist may be longer. Some countries require proof of vaccination for entry, while others strongly recommend extra protection based on health risks. Common examples include:

  • Hepatitis A & B: For areas where food and water sanitation may be less reliable.
  • Typhoid: Recommended for travel in parts of Asia, Africa, and Latin America.
  • Yellow Fever: Required for entry into certain African and South American countries.
  • Traveler’s Diarrhea & Cholera: Not always required, but sometimes advised for high-risk destinations.
     

Plan ahead: many vaccines take at least 2 weeks to become effective, and some require multiple doses.

 

Timing, Refills, and Smart Prep

Vaccines aren’t the only thing to plan for—travel health prep is about the whole picture.

  • Start Early: See your provider 4–6 weeks before your trip to give vaccines time to work.
  • Check Prescriptions: Make sure you have enough of your daily medications packed to last the entire trip plus a few extra days.
  • Ask About Travel Medications: Depending on your destination, you may need malaria prevention, altitude medication, or motion sickness prescriptions.
  • Use Telehealth as Backup: Even if you forget to prepare, virtual care can guide you to the right vaccines or prescribe necessary meds fast.

How CallOnDoc Can Help

At CallOnDoc, we take the stress out of travel prep. Our providers can review your health needs, guide you on which vaccines to get, and ensure you have all the prescriptions you need before you head out. That way, you can focus on enjoying the holidays—not worrying about getting sick.

👉 Healthcare that fits in your pocket, not your calendar.

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Shelly House, FNP,

Shelly House, FNP, is a Family Nurse Practitioner and Call-On-Doc’s trusted medical education voice. With extensive experience in telehealth and patient-centered care, Ms. House is dedicated to making complex health topics simple and accessible. Through evidence-based content, provider collaboration, and a passion for empowering patients, her mission is to break down barriers to healthcare by delivering clear, compassionate, and practical medical guidance.

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