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Current Guidelines for STD Testing: What You Should Know

Published on Dec 17, 2025 | 10:34 AM

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Sexually transmitted diseases (STDs), also called sexually transmitted infections (STIs), are incredibly common — and most people who have one don’t know it right away.

That’s why routine testing is one of the most important tools we have for protecting sexual health. Over the past several years, STD testing guidelines have been updated to reflect new research, better diagnostics, and a clearer understanding of how infections spread.

If you’re unsure when to get tested, what to test for, or how often, you’re not alone. Let’s break down the current STD testing guidelines, what they mean for you, and how testing fits into real life — not just textbook recommendations.

Why STD Testing Matters (Even Without Symptoms)

One of the biggest misconceptions about STDs is that you’ll always “feel something.”

In reality:

  • Many STDs cause no symptoms at all

  • Others cause very mild or nonspecific symptoms

  • You can feel completely healthy and still transmit an infection

Routine testing:
✔ protects your health
✔ protects your partners
✔ prevents long-term complications
✔ allows early, easier treatment

Testing isn’t about judgment — it’s about information.

General STD Testing Recommendations for Sexually Active Adults

At least once a year, testing is recommended for:

  • anyone who is sexually active and under age 25

  • adults with new or multiple sexual partners

  • people who do not consistently use barrier protection

Annual testing typically includes:

  • chlamydia

  • gonorrhea

  • HIV

  • syphilis (based on risk)

STD Testing Guidelines by Infection

Chlamydia & Gonorrhea

Who should be tested:

  • all sexually active women under 25 (at least annually)

  • women 25 and older with new or multiple partners

  • men who have sex with men (MSM): at least annually

  • anyone with symptoms or a known exposure

Testing sites matter:

  • urine tests

  • vaginal, cervical, rectal, or throat swabs depending on sexual activity

Many infections are missed if testing is limited to urine alone.

HIV

Current guidelines recommend:

  • at least one HIV test for all adults ages 13–64

  • annual testing for those at ongoing risk

  • more frequent testing (every 3–6 months) for higher-risk individuals

HIV testing is routine, confidential, and highly accurate.

Syphilis

Testing is recommended for:

  • pregnant individuals (early and sometimes again later in pregnancy)

  • men who have sex with men (at least annually)

  • individuals with multiple partners

  • anyone diagnosed with another STD

  • people with unexplained rashes or sores

Syphilis rates have increased significantly in recent years, making screening more important than ever.

Hepatitis B & C

Hepatitis B testing is recommended for:

  • unvaccinated adults at risk

  • people with multiple sexual partners

  • those with a history of STDs

Hepatitis C testing is now recommended:

  • at least once for all adults

  • more often for those with risk factors

Herpes (HSV-1 and HSV-2)

This is where guidelines are often misunderstood.

Routine blood testing is not recommended for everyone.

Why?

  • Blood tests cannot tell where the infection is located

  • Many people have HSV-1 from childhood

  • False positives can cause unnecessary anxiety

Herpes testing is recommended when:

  • there are active sores (swab testing)

  • symptoms are present

  • a partner has known herpes and testing is part of a shared decision

HPV (Human Papillomavirus)

HPV testing is done through:

  • Pap smears and HPV screening — not blood tests

Routine screening guidelines depend on:

  • age

  • cervix status

  • prior results

Most sexually active people will be exposed to HPV at some point, and most clear it naturally.

When You Should Get Tested Outside of Routine Screening

You should seek STD testing if:

  • you have a new sexual partner

  • a partner tests positive

  • you have symptoms (burning, discharge, sores, pain, itching)

  • a condom breaks or protection wasn’t used

  • you’re starting or ending a relationship

  • you want peace of mind

There’s no “wrong” reason to get tested.

Understanding Testing Windows (Why Timing Matters)

Every STD has a window period — the time between exposure and when a test becomes reliable.

Examples:

  • chlamydia & gonorrhea: ~5–7 days

  • HIV (modern tests): 2–6 weeks

  • syphilis: 3–6 weeks

  • herpes blood tests: several weeks to months

Testing too early can lead to false reassurance.
A clinician can help you time testing correctly.

STD Testing Is About Health — Not Assumptions

Current guidelines emphasize:
✔ routine testing as preventive care
✔ normalizing STD screening
✔ removing stigma
✔ encouraging open conversations

Getting tested does not mean:

  • you did something wrong

  • your partner was unfaithful

  • you’re irresponsible

It means you’re informed.

How CallOnDoc Makes STD Testing Easier

CallOnDoc follows current, evidence-based STD testing guidelines and makes care accessible, private, and judgment-free.

We help with:

  • deciding what tests you actually need

  • timing tests correctly

  • explaining results clearly

  • treatment when needed

  • follow-up testing

  • partner considerations

  • discreet care from home

You deserve accurate information — not confusion or fear.

The Bottom Line

STD testing guidelines have evolved to be:
✔ smarter
✔ more personalized
✔ less stigmatizing
✔ focused on prevention

Whether you test routinely, after a new partner, or just for peace of mind, testing is a form of self-care.

Knowledge protects you — and CallOnDoc is here to help.

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Shelly House, FNP,

Shelly House, FNP, is a Family Nurse Practitioner and Call-On-Doc’s trusted medical education voice. With extensive experience in telehealth and patient-centered care, Ms. House is dedicated to making complex health topics simple and accessible. Through evidence-based content, provider collaboration, and a passion for empowering patients, her mission is to break down barriers to healthcare by delivering clear, compassionate, and practical medical guidance.

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