Published on Dec 17, 2025 | 10:34 AM
Sexually transmitted diseases (STDs), also called sexually transmitted infections (STIs), are incredibly common — and most people who have one don’t know it right away.
That’s why routine testing is one of the most important tools we have for protecting sexual health. Over the past several years, STD testing guidelines have been updated to reflect new research, better diagnostics, and a clearer understanding of how infections spread.
If you’re unsure when to get tested, what to test for, or how often, you’re not alone. Let’s break down the current STD testing guidelines, what they mean for you, and how testing fits into real life — not just textbook recommendations.
One of the biggest misconceptions about STDs is that you’ll always “feel something.”
In reality:
Many STDs cause no symptoms at all
Others cause very mild or nonspecific symptoms
You can feel completely healthy and still transmit an infection
Routine testing:
✔ protects your health
✔ protects your partners
✔ prevents long-term complications
✔ allows early, easier treatment
Testing isn’t about judgment — it’s about information.
anyone who is sexually active and under age 25
adults with new or multiple sexual partners
people who do not consistently use barrier protection
Annual testing typically includes:
chlamydia
gonorrhea
HIV
syphilis (based on risk)
Who should be tested:
all sexually active women under 25 (at least annually)
women 25 and older with new or multiple partners
men who have sex with men (MSM): at least annually
anyone with symptoms or a known exposure
Testing sites matter:
urine tests
vaginal, cervical, rectal, or throat swabs depending on sexual activity
Many infections are missed if testing is limited to urine alone.
Current guidelines recommend:
at least one HIV test for all adults ages 13–64
annual testing for those at ongoing risk
more frequent testing (every 3–6 months) for higher-risk individuals
HIV testing is routine, confidential, and highly accurate.
Testing is recommended for:
pregnant individuals (early and sometimes again later in pregnancy)
men who have sex with men (at least annually)
individuals with multiple partners
anyone diagnosed with another STD
people with unexplained rashes or sores
Syphilis rates have increased significantly in recent years, making screening more important than ever.
Hepatitis B testing is recommended for:
unvaccinated adults at risk
people with multiple sexual partners
those with a history of STDs
Hepatitis C testing is now recommended:
at least once for all adults
more often for those with risk factors
This is where guidelines are often misunderstood.
Routine blood testing is not recommended for everyone.
Why?
Blood tests cannot tell where the infection is located
Many people have HSV-1 from childhood
False positives can cause unnecessary anxiety
Herpes testing is recommended when:
there are active sores (swab testing)
symptoms are present
a partner has known herpes and testing is part of a shared decision
HPV testing is done through:
Pap smears and HPV screening — not blood tests
Routine screening guidelines depend on:
age
cervix status
prior results
Most sexually active people will be exposed to HPV at some point, and most clear it naturally.
You should seek STD testing if:
you have a new sexual partner
a partner tests positive
you have symptoms (burning, discharge, sores, pain, itching)
a condom breaks or protection wasn’t used
you’re starting or ending a relationship
you want peace of mind
There’s no “wrong” reason to get tested.
Every STD has a window period — the time between exposure and when a test becomes reliable.
Examples:
chlamydia & gonorrhea: ~5–7 days
HIV (modern tests): 2–6 weeks
syphilis: 3–6 weeks
herpes blood tests: several weeks to months
Testing too early can lead to false reassurance.
A clinician can help you time testing correctly.
Current guidelines emphasize:
✔ routine testing as preventive care
✔ normalizing STD screening
✔ removing stigma
✔ encouraging open conversations
Getting tested does not mean:
you did something wrong
your partner was unfaithful
you’re irresponsible
It means you’re informed.
CallOnDoc follows current, evidence-based STD testing guidelines and makes care accessible, private, and judgment-free.
We help with:
deciding what tests you actually need
timing tests correctly
explaining results clearly
treatment when needed
follow-up testing
partner considerations
discreet care from home
You deserve accurate information — not confusion or fear.
STD testing guidelines have evolved to be:
✔ smarter
✔ more personalized
✔ less stigmatizing
✔ focused on prevention
Whether you test routinely, after a new partner, or just for peace of mind, testing is a form of self-care.
Knowledge protects you — and CallOnDoc is here to help.
Shelly House, FNP, is a Family Nurse Practitioner and Call-On-Doc’s trusted medical education voice. With extensive experience in telehealth and patient-centered care, Ms. House is dedicated to making complex health topics simple and accessible. Through evidence-based content, provider collaboration, and a passion for empowering patients, her mission is to break down barriers to healthcare by delivering clear, compassionate, and practical medical guidance.
Risks Associated With Leaving STDs Untreated
Leaving sexually transmitted diseases (STDs) untreated can have serious consequences, as many STDs can lead to long-term health complications such as infertility, pelvic inflammatory disease, and an increased risk of HIV transmission. Additionally, some STDs can progress silently without noticeable symptoms, emphasizing the importance of early detection and treatment to prevent further health risks and potential transmission to others.
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Read MoreGet Treated for STDs without Testing
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Specializing in asynchronous consultations, an online text-style visit, our board-certified medical providers offer STD treatment online for a reduced cost that is 100% private and from the comfort of home on your phone or computer!
Simply select a condition and fill out the medical intake form. Then, we'll review and prescribe the appropriate treatment plan that is available for pick-up at any US pharmacy in 1-2 hours.
Not sure what STD you have? No problem, we can still help treat you. On our STD page, select "unsure" and answer a few questions about your symptoms. Our medical providers will know what treatment option is best based on the medical and sexual history as well as other information you can provide.
Does your partner also need treatment? We can help keep both of you sexually healthy and provide 50% off partner treatment.
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Read MoreSTD Symptoms in Men
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Understanding common symptoms, practicing prevention strategies, and getting tested regularly are essential for maintaining sexual health.
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Read MoreRisks Associated With Leaving STDs Untreated
Leaving sexually transmitted diseases (STDs) untreated can have serious consequences, as many STDs can lead to long-term health complications such as infertility, pelvic inflammatory disease, and an increased risk of HIV transmission. Additionally, some STDs can progress silently without noticeable symptoms, emphasizing the importance of early detection and treatment to prevent further health risks and potential transmission to others.
Jun 29, 2022 | 3:37 PM
Get Treated for STDs without Testing
Most people typically assume that when it comes to STD treatment, you’ll need to go to a doctor’s office and get tested. Not only can the entire process be unnerving, but going into a doctor's office can be uncomfortable, timely, and expensive. However, there is now a more accessible option for STD treatment with telemedicine. Call-On-Doc provides same-day relief for STD symptoms without the hassle of appointments, lab testing, and face-to-face visits.
Specializing in asynchronous consultations, an online text-style visit, our board-certified medical providers offer STD treatment online for a reduced cost that is 100% private and from the comfort of home on your phone or computer!
Simply select a condition and fill out the medical intake form. Then, we'll review and prescribe the appropriate treatment plan that is available for pick-up at any US pharmacy in 1-2 hours.
Not sure what STD you have? No problem, we can still help treat you. On our STD page, select "unsure" and answer a few questions about your symptoms. Our medical providers will know what treatment option is best based on the medical and sexual history as well as other information you can provide.
Does your partner also need treatment? We can help keep both of you sexually healthy and provide 50% off partner treatment.
Apr 18, 2023 | 1:20 PM
STD Symptoms in Men
STIs and STDs, which are sometimes collectively referred to as STDs, are more common in men than many realize. Many men assume they would know if they had an STD, but some infections remain silent for weeks, months, or even years. Without testing and treatment, an infection can be unknowingly transmitted or lead to serious health complications like infertility or chronic pain
Understanding common symptoms, practicing prevention strategies, and getting tested regularly are essential for maintaining sexual health.
Feb 06, 2025 | 10:10 AM
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