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GLP-1 Medications and Hair Loss: What’s Really Going On?

Published on Dec 02, 2025 | 2:41 PM

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As medications like semaglutide (Ozempic®, Wegovy®) and tirzepatide (Mounjaro®, Zepbound®) become more common for weight management, many people are asking:
“Do GLP-1 medications cause hair loss?”

The honest answer is that hair loss can happen while taking GLP-1s, but the medication itself is rarely the direct cause. Instead, most shedding is linked to changes happening in the body during rapid weight loss, not damage to the follicles.

Below is what we know — and what you can do to protect your hair du

🧬 Why Hair Loss Happens During GLP-1 Therapy

The type of hair loss most people experience is called telogen effluvium, a temporary shift in the hair cycle that causes shedding 2–3 months after a physical or emotional stressor.
GLP-1 medications can trigger the situation, but they don’t damage the hair root. The body is simply adjusting to rapid metabolic changes.

Here are the most common contributors:

1️⃣ Rapid Weight Loss

When weight drops quickly, the body re-prioritizes energy away from non-essential systems like hair growth. This doesn’t mean damage has occurred — just that the follicles enter a rest phase. Shedding typically appears later, even after the weight loss has slowed.

2️⃣ Low Protein Intake

Because GLP-1s decrease appetite, many people unintentionally eat less protein.
Hair is made almost entirely of keratin (a protein), so inadequate intake can increase shedding.

Common signs you’re not getting enough include brittle nails, fatigue, and feeling full quickly.

3️⃣ Nutrient Deficiencies

Smaller meals or skipped meals can lead to low levels of:

  • iron

  • zinc

  • vitamin D

  • biotin

  • B vitamins

These nutrients play a key role in follicle growth. Even mild deficiencies can cause noticeable thinning.

4️⃣ Stress and Hormonal Shifts

Weight loss — even healthy weight loss — is a physiological stressor.
Changes in routine, sleep, hydration, and blood sugar can elevate stress hormones, which disrupt the normal hair cycle.

This is why some people see increased shedding even when nutrition seems balanced.

5️⃣ Underlying Conditions

Sometimes hair loss shows up while taking GLP-1s but was already developing due to:

  • thyroid disorders

  • anemia

  • genetics

  • menopause

  • postpartum shifts

  • autoimmune conditions

The timing can make it seem like the medication caused it, even when something else was already underway.

🌱 The Good News: GLP-1 Hair Loss Is Usually Temporary

With telogen effluvium, the follicles aren’t damaged. They simply “reset” and return to normal growth once the stressor stabilizes. Most people see regrowth within 3–6 months.

This means hair loss during GLP-1 therapy is reversible — and often preventable.

💡 How to Support Hair Health While Taking GLP-1s

Here is a mix of practical strategies that genuinely help:

✔️ Prioritize Protein

Aim for 60–90 grams per day, based on age, size, and activity level.
Protein shakes, yogurt, eggs, tofu, and lean meats are easy wins — especially if you get full quickly.

✔️ Take a Daily Multivitamin

Choose one that includes iron, zinc, vitamin D, biotin, and B12.
These support healthy hair cycling and offset low-intake days.

✔️ Eat Regularly — Even Without Hunger

GLP-1s work by reducing appetite, so forgetting to eat becomes common.
Small, balanced meals every 3–4 hours help avoid nutrient dips that trigger shedding.

✔️ Adjust Weight Loss Pace If Needed

If weight is dropping very fast, talk to your provider about adjusting dosage.
A gentler pace puts less stress on the hair cycle.

✔️ Stay Hydrated

Dehydration affects scalp health and increases breakage.
Set small hydration goals throughout the day to keep it manageable.

✔️ Be Gentle With Your Hair

During a shedding phase, reduce heat styling, tight hairstyles, and chemical treatments.

🩺 When to Seek Medical Evaluation

Look for medical support if you notice:

  • patchy or sudden bald spots

  • shedding that lasts longer than 6 months

  • scalp pain, redness, or inflammation

  • severe fatigue or cold intolerance (possible thyroid issues)

  • heavy menstrual periods or dizziness (possibly low iron)

These may indicate another condition that needs treatment.

🩺 How CallOnDoc Can Help

CallOnDoc providers can:

  • determine whether hair loss is truly medication-related

  • check for nutrient deficiencies

  • evaluate thyroid or anemia concerns

  • adjust your GLP-1 plan for gentler weight loss

  • recommend supplements that support healthy hair

  • create a nutrition strategy that keeps you feeling strong

Your health journey shouldn’t come at the cost of your confidence — and with the right support, it doesn’t have to.

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Shelly House, FNP,

Shelly House, FNP, is a Family Nurse Practitioner and Call-On-Doc’s trusted medical education voice. With extensive experience in telehealth and patient-centered care, Ms. House is dedicated to making complex health topics simple and accessible. Through evidence-based content, provider collaboration, and a passion for empowering patients, her mission is to break down barriers to healthcare by delivering clear, compassionate, and practical medical guidance.

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