Published on Aug 02, 2026 | 11:53 AM
Many people have heard that they should throw away their toothbrush immediately after getting sick.
But is that actually necessary?
For most common viral illnesses, such as the common cold, influenza, and COVID-19, there is little evidence that keeping your toothbrush will make you sick again after you've recovered. Once your immune system has cleared the infection, you're generally protected against that same strain of virus for a period of time.
However, there are situations where replacing your toothbrush is a good idea—especially if the bristles are worn, after certain bacterial infections like strep throat, or if the toothbrush has become visibly contaminated.
After recovering from strep throat (after you've been on antibiotics for at least 24 hours)
If the bristles are frayed or worn
Every 3–4 months as part of routine oral care
After visible contamination with blood or bodily fluids
After mold growth or improper storage
Persistent sore throat
Fever that returns after improving
Difficulty swallowing
Swollen lymph nodes
White patches in the throat
Symptoms lasting longer than expected
If you've ever recovered from a cold and immediately thrown away your toothbrush, you're not alone.
It's one of the most common pieces of health advice shared by family members, friends, and social media.
But like many health myths, there's only part of the story that's true.
Understanding how viruses and bacteria behave can help you decide when replacing your toothbrush actually makes sense.
For most viral illnesses, the answer is probably not.
After your immune system fights off a virus like the common cold or influenza, it develops antibodies that help protect you from becoming infected with that same virus again for a period of time.
Because of this immune response, the virus left on your toothbrush is unlikely to cause you to immediately become sick again.
In addition, most respiratory viruses do not survive indefinitely on toothbrush bristles.
The type of illness you had matters.
Common viral illnesses include:
Common cold
Influenza (flu)
COVID-19
RSV
Many viral sore throats
These illnesses generally do not require replacing your toothbrush solely to prevent reinfection.
However, bacterial infections can be different.
For example, if you've been diagnosed with strep throat, many healthcare providers recommend replacing your toothbrush after you've been taking antibiotics for at least 24 hours to reduce the chance of continued exposure to bacteria.
Early in the COVID-19 pandemic, many people were advised to replace toothbrushes after infection.
Current evidence does not strongly support replacing your toothbrush solely because you had COVID-19.
Once you've recovered and your immune system has responded to the virus, reinfection from your own toothbrush is considered unlikely.
Good oral hygiene and routine toothbrush replacement remain the most important recommendations.
Even if illness isn't the reason, toothbrushes should not last forever.
Dental professionals generally recommend replacing your toothbrush:
Every three to four months
When bristles become frayed
After significant contamination
If mold develops
After recovering from strep throat
A worn toothbrush simply doesn't clean your teeth as effectively.
Proper storage is more important than many people realize.
To reduce bacterial growth:
Rinse your toothbrush thoroughly after each use.
Store it upright so it can air dry.
Avoid closed containers that trap moisture.
Do not allow toothbrush heads to touch one another.
Replace toothbrushes regularly.
Contrary to popular belief, soaking your toothbrush in mouthwash or disinfectants is generally unnecessary.
Many people believe they keep getting sick because they didn't replace their toothbrush.
In reality, repeat illnesses are much more commonly caused by:
Exposure to new viruses
Household transmission
School or workplace exposure
Seasonal respiratory viruses
Allergies mistaken for infection
Your toothbrush is rarely the reason someone becomes ill again.
Most viral illnesses improve within several days to two weeks.
However, certain symptoms warrant medical evaluation.
Fever that returns
Difficulty swallowing
Severe sore throat
Swollen lymph nodes
White patches on the tonsils
Difficulty breathing
Symptoms that continue worsening
These symptoms may indicate a bacterial infection or another condition requiring treatment.
Mild lingering cough
Improving sore throat
Mild fatigue
Occasional nasal congestion
Gradually improving energy
These symptoms often improve over time without additional treatment.
High fever
Difficulty breathing
Persistent severe sore throat
Difficulty swallowing saliva
Significant neck swelling
Symptoms worsening after initially improving
These symptoms may require additional evaluation.
Usually no. There is little evidence that keeping your toothbrush after a viral cold will cause you to become sick again.
Yes. Many healthcare providers recommend replacing your toothbrush after you have been taking antibiotics for at least 24 hours.
Some viruses can survive on surfaces for a limited time, but they generally do not remain infectious indefinitely, and reinfection from your own toothbrush appears to be unlikely.
Most dentists recommend replacing your toothbrush every three to four months or sooner if the bristles become worn.
Routine rinsing and proper air drying are generally sufficient. Special disinfecting products are not usually necessary.
If you're recovering from an illness and aren't sure whether your symptoms are improving normally or could indicate a bacterial infection, CallOnDoc can help.
CallOnDoc offers convenient online evaluations for sore throat, strep throat, influenza, COVID-19, upper respiratory infections, sinus infections, and other common illnesses.
Licensed providers can review your symptoms, determine whether testing or treatment may be appropriate, and recommend a care plan based on your medical history and current condition.
Whether you're recovering at home, traveling, or unable to visit a clinic, expert medical care may be available wherever you have internet access.
For most viral illnesses, replacing your toothbrush is more myth than medical necessity.
While routine toothbrush replacement remains important for good oral health, there is little evidence that your toothbrush will cause you to catch the same cold or flu again after you've recovered.
The exception is certain bacterial infections, such as strep throat, where replacing your toothbrush after starting antibiotics may be beneficial.
Maintaining good oral hygiene, storing your toothbrush properly, and replacing it every few months are still the best ways to keep your mouth healthy.
Shelly House, FNP, is a Family Nurse Practitioner and Call-On-Doc’s trusted medical education voice. With extensive experience in telehealth and patient-centered care, Ms. House is dedicated to making complex health topics simple and accessible. Through evidence-based content, provider collaboration, and a passion for empowering patients, her mission is to break down barriers to healthcare by delivering clear, compassionate, and practical medical guidance.
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